بحث بيانات أعضاء هيئة التدريس - جامعة الزقازيق

/ بحث بيانات أعضاء هيئة التدريس - جامعة الزقازيق

لايوجد

الموقع الشخصى

جلال يحيى عبدالرحيم متولى

الكلية الصيدلة - القسم الميكروبيولوجى والمناعة

الدرجات العلمية

بكالوريوس فى الميكروبيولوجي والمناعه, -جامعة الزقازيق [2006]
دكتوراه فى الميكروبيولوجي والمناعه, -جامعة برشلونة [2016]

الحالة الوظيفية الحالية :

قائم باجازة خاصة

التدرج الوظيفى الأكاديمى

معيد : 2/10/2006
مدرس : 31/5/2016
أستاذ مساعد : 28/12/2021
استاذ مساعد لقب علمى : 28/12/2021

الأبحاث العلمية

1 - Electrocardiographic and histopathological characterizations of diabetic cardiomyopathy in rats (1443).

2 - In silico screening of potent inhibitors against COVID-19 key targets from a library of FDA-approved drugs (1443).

3 - Soil-Associated Bacillus Species: A Reservoir of Bioactive Compounds with Potential Therapeutic Activity against Human Pathogens (1442).

4 - Optimizing Eco-Friendly Degradation of Polyvinyl Chloride (PVC) Plastic Using Environmental Strains of Malassezia Species and Aspergillus fumigatus (1445).

5 - Transcriptomic balance and optimal growth are determined by cell size (1446).

6 - Design and synthesis of novel chloropyridazine hybrids as promising anticancer agents acting by apoptosis induction and PARP-1 inhibition through a molecular hybridization strategy (1445).

7 - Global, regional, and national incidence and mortality burden of non-COVID-19 lower respiratory infections and aetiologies, 1990-2021: a systematic analysis from the Global Burden of Disease Study 2021 (1446).

8 - The Link between Occurrence of Class I Integron and Acquired Aminoglycoside Resistance in Clinical MRSA Isolates (1442).

9 - Role of Ganetespib, an HSP90 Inhibitor, in Cancer Therapy: From Molecular Mechanisms to Clinical Practice (1444).

10 - Pharmaceutical polymers and P-glycoprotein: Current trends and possible outcomes in drug delivery (1444).

11 - Emerging Approach for the Application of Hibiscus sabdariffa Extract Ointment in the Superficial Burn Care (1443).

12 - Multifunctional Spirogyra-hyalina-Mediated Barium Oxide Nanoparticles (BaONPs): Synthesis and Applications (1445).

13 - Optimizing Eco-Friendly Degradation of Polyvinyl Chloride (PVC) Plastic Using Environmental Strains of Malassezia Species and Aspergillus fumigatus (1445).

14 - The battle against dental caries: defeating bioflm formed by bacterial isolates using vanillin and plant essential oils: in vitro and ex vivo approaches (1446).

15 - Genome Analysis of Pseudomonas aeruginosa Strains from Chronically Infected Patients with High Levels of Persister Formation (1444).

16 - A Whi7-anchored loop controls the G1 Cdk-cyclin complex at start. (1435).

17 - Mitigating diabetes-related complications: Empowering metformin with cholecalciferol and taurine supplementation in type 2 diabetic rats (1446).

18 - Phospho-regulation of the Shugoshin - Condensin interaction at the centromere in budding yeast (1441).

19 - Global, regional, and national burden of disorders affecting the nervous system, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021 (1445).

20 - In vitro activity of celastrol in combination with thymol against carbapenem-resistant Klebsiella pneumoniae isolates (1444).

21 - Isolation, partial characterization, therapeutic, and safety evaluation of carbapenem-resistant Acinetobacter baumannii lytic phage in a mouse model (1446).

22 - The battle against dental caries: defeating biofilm formed by bacterial isolates using vanillin and plant essential oils: in vitro and ex vivo approaches (1446).

23 - Bacteria-powered self-healing concrete: Breakthroughs, challenges, and future prospects (1446).

24 - From Isolation to Application: Utilising Phage‐Antibiotic Synergy in Murine Bacteremia Model to Combat Multidrug‐Resistant Enterococcus faecalis (1446).

25 - Robust Antiviral Activity of Santonica Flower Extract (Artemisia cina) against Avian and Human Influenza A Viruses: In Vitro and Chemoinformatic Studies (1444).

26 - In-silico screening of naturally derived phytochemicals against SARS-CoV Main protease (1443).

27 - Ameliorative Effect of Dabigatran on CFA-Induced Rheumatoid Arthritis via Modulating Kallikrein-Kinin System in Rats (1444).

28 - Modulation of cell cycle progression and chromatin dynamic as tolerance mechanisms to salinity and drought stress in maize (1442).

29 - Unlocking the Full Potential of SGLT2 Inhibitors: Expanding Applications beyond Glycemic Control (1444).

30 - COVID-19 surveillance in wastewater: An epidemiological tool for the monitoring of SARS-CoV-2 (1444).

31 - Detection and health risk assessment of toxic heavy metals in chilled and frozen meat collected from Sharkia province in Egypt (1445).

32 - Global pattern, trend, and cross-country inequality of early musculoskeletal disorders from 1990 to 2019, with projection from 2020 to 2050 (1446).

33 - Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 (1445).

34 - A Novel Combination Therapy Using Rosuvastatin and Lactobacillus Combats Dextran Sodium Sulfate-Induced Colitis in High-Fat Diet-Fed Rats by Targeting the TXNIP/NLRP3 Interaction and Influencing Gut Microbiome Composition (1442).

35 - Cell cycle machinery in oncology: A comprehensive review of therapeutic targets (1445).

36 - Phenotypic, molecular, and in silico characterization of coumarin as carbapenemase inhibitor to fight carbapenem-resistant Klebsiella pneumoniae (1445).

37 - Eco-smart biocontrol strategies utilizing potent microbes for sustainable management of phytopathogenic diseases (1446).

38 - In silico screening of potent bioactive compounds from honeybee products against COVID-19 target enzymes (1442).

39 - Emerging Role of GLP-1 Agonists in Obesity: A Comprehensive Review of Randomised Controlled Trials (1444).

40 - Innovative challenge for the inhibition of hepatocellular carcinoma progression by combined targeting of HSP90 and STAT3/HIF-1α signaling (1444).

41 - Mitigating diabetes-related complications: Empowering metformin with cholecalciferol and taurine supplementation in type 2 diabetic rats (1446).

42 - Interleukins (Cytokines) as Biomarkers in Colorectal Cancer: Progression, Detection, and Monitoring (1444).

43 - Inntags: small self-structured epitopes for innocuous protein tagging. (1436).

44 - Cdc48/p97 segregase is modulated by cyclin‐dependent kinase to determine cyclin fate during G1 progression (1439).

45 - Profiling the physiological pitfalls of anti‐hepatitis C direct‐acting agents in budding yeast (1443).

46 - The Supportive Role of NSC328382, a P2X7R Antagonist, in Enhancing the Inhibitory Effect of CRID3 on NLRP3 Inflammasome Activation in Rats with Dextran Sodium Sulfate-Induced Colitis (1442).

47 - Recent Advances in the Development of Metal/Metal Oxide Nanoparticle and Antibiotic Conjugates (MNP–Antibiotics) to Address Antibiotic Resistance: Review and Perspective (1446).

48 - Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 (1446).

49 - Revolutionizing Treatment Strategies for Autoimmune and Inflammatory Disorders: The Impact of Dipeptidyl-Peptidase 4 Inhibitors (1445).

50 - Phenotypic, molecular, and in silico characterization of coumarin as carbapenemase inhibitor to fght carbapenem-resistant Klebsiella pneumoniae (1445).

51 - Competition in the chaperone-client network subordinates cell-cycle entry to growth and stress (1440).

52 - In vitro activity of celastrol in combination with thymol against carbapenem-resistant Klebsiella pneumoniae isolates (1444).

53 - Coomassie brilliant blue G-250 dye attenuates bleomycin-induced lung fibrosis by regulating the NF-κB and NLRP3 crosstalk: A novel approach for filling an unmet medical need (1443).

54 - The dynamic interplay between AMPK/NFκB signaling and NLRP3 is a new therapeutic target in inflammation: Emerging role of dapagliflozin in overcoming lipopolysaccharide-mediated lung injury (1443).

55 - In silico screening of potent inhibitors against COVID-19 key targets from a library of FDA-approved drugs (1443).

56 - Sublinear scaling of the cellular proteome with ploidy (1444).

57 - GC-MS Analysis and Microbiological Evaluation of Caraway Essential Oil as a Virulence Attenuating Agent against Pseudomonas aeruginosa (1444).

58 - Regulatory and pathogenic mechanisms in response to iron deficiency and excess in fungi (1445).

59 - Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019 (1445).

60 - Molecular Understanding of ACE-2 and HLA-Conferred Differential Susceptibility to COVID-19: Host-Directed Insights Opening New Windows in COVID-19 Therapeutics (1444).

61 - Identification of Natural Lead Compounds against Hemagglutinin-Esterase Surface Glycoprotein in Human Coronaviruses Investigated via MD Simulation, Principal Component Analysis, Cross-Correlation, H-Bond Plot and MMGBSA (1444).

62 - The Breadth of Bacteriophages Contributing to the Development of the Phage-Based Vaccines for COVID-19: An Ideal Platform to Design the Multiplex Vaccine (1444).

63 - Genome Analysis of Pseudomonas aeruginosa Strains from Chronically Infected Patients with High Levels of Persister Formation (1444).

64 - Electrocardiographic and histopathological characterizations of diabetic cardiomyopathy in rats (1443).

65 - Robust Antiviral Activity of Santonica Flower Extract (Artemisia cina) against Avian and Human Influenza A Viruses: In Vitro and Chemoinformatic Studies (1444).

66 - Blocking prostanoid receptors switches on multiple immune responses and cascades of inflammatory signaling against larval stages in snail fever (1443).

67 - Zingiber officinale rhizome extracts mediated ni nanoparticles and its promising biomedical and environmental applications (1445).

68 - Phytoestrogen β-Sitosterol Exhibits Potent In Vitro Antiviral Activity against Influenza A Viruses (1444).

69 - The Unusual Architecture of RNA-Dependent RNA Polymerase (RdRp)’s Catalytic Chamber Provides a Potential Strategy for Combination Therapy against COVID-19 (1444).

70 - Unlocking the therapeutic potential of Nigella sativa extract: phytochemical analysis and revealing antimicrobial and antioxidant marvels (1446).

71 - Global estimates on the number of people blind or visually impaired by Uncorrected Refractive Error: a meta-analysis from 2000 to 2020 (1445).

72 - Global pattern, trend, and cross-country inequality of early musculoskeletal disorders from 1990 to 2019, with projection from 2020 to 2050 (1446).

73 - Streptomyces Paradigm in Anticancer Therapy: A State-of-the Art Review (1445).

74 - Peroxiredoxins couple metabolism and cell division in an ultradian cycle (1442).

75 - The Link between Occurrence of Class I Integron and Acquired Aminoglycoside Resistance in Clinical MRSA Isolates (1442).

76 - Diabetes Mellitus Secondary to Endocrine Diseases: An Update of Diagnostic and Treatment Particularities (1445).

77 - Antibacterial and Antibiofilm Activity of Ficus carica-Mediated Calcium Oxide (CaONPs) Phyto-Nanoparticles (1445).

78 - Phenotypic, molecular, and in silico characterization of coumarin as carbapenemase inhibitor to fight carbapenem-resistant Klebsiella pneumoniae (1445).

79 - Fighting against the second wave of COVID-19: Can honeybee products help protect against the pandemic? (1442).

80 - Stress granules display bistable dynamics modulated by Cdk (1442).

81 - A new framework for novel analogues of pazopanib as potent and selective human carbonic anhydrase inhibitors: Design, repurposing rational, synthesis, crystallographic, in vivo and in vitro biological assessments (1446).

82 - In-silico screening of naturally derived phytochemicals against SARS-CoV Main protease (1443).

83 - Coronavirus Disease (COVID-19) Control between Drug Repurposing and Vaccination: A Comprehensive Overview (1443).

84 - Exosomes in Alzheimer’s Disease: From Being Pathological Players to Potential Diagnostics and Therapeutics (1443).

85 - Combination of Meropenem and Zinc Oxide Nanoparticles; Antimicrobial Synergism, Exaggerated Antibiofilm Activity, and Efficient Therapeutic Strategy against Bacterial Keratitis (1444).

المجالات البحثية

Microbiology, immunology and Molecular biology