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Israa Abdallah Mostafa Sliem

Faculty pharmacy - Department Pharmaceutical Organic Chemistry Department

Scientific degrees

BSc In NULL, [2009]
MSc In NULL, [2015]
PhD In NULL, [2020]

الحالة الوظيفية الحالية :

قائم بالعمل

Academic Jobs

معيد : 23/11/2009
Doctor Assisant : 26/1/2016
Doctor : 23/2/2021

Publications

1 - Design, synthesis, antimicrobial, and DNA gyrase inhibitory properties of fluoroquinolone–dichloroacetic acid hybrids (2020).

2 - An Efficient Greener Approach for N-Acylation of Amines in Water Using Benzotriazole Chemistry (2020).

3 - In Vitro Antimycobacterial Activity and Physicochemical Characterization of Diaryl Ether Triclosan Analogues as Potential InhA Reductase Inhibitors (2020).

4 - New Pyrazine Conjugates: Synthesis, Computational Studies, and Antiviral Properties against SARS-CoV-2 (2021).

5 - New quinoline-triazole conjugates: Synthesis, and antiviral properties against SARS-CoV-2 (2021).

6 - Development of Isatin-Based Schiff Bases Targeting VEGFR-2 Inhibition: Synthesis, Characterization, Antiproliferative Properties, and QSAR Studies (2022).

7 - DMF-DMA catalyzed Synthesis, molecular docking, in-vitro, in-silico design, and binding free energy studies of novel thiohydantoin derivatives as antioxidant and antiproliferative agents targeting EGFR tyrosine kinase and aromatase cytochrome P450 enzyme (2024).

8 - Synthesis, cytotoxic activity, molecular docking, molecular dynamics simulations, and ADMET studies of novel spiropyrazoline oxindoles based on domino Knoevenagel–Michael cyclization as potent non-toxic anticancer agents targeting β-tubulin and EGFR, with anti-MRSA activity (2025).

9 - Design, eco-friendly synthesis, and molecular docking studies of isatin hybrids as promising therapeutic agents (anticancer, anticholinesterase inhibitor, α-glucosidase inhibitor, and anti-MRSA) (2025).

10 - Microwave-assisted one-pot green synthesis, ADMET profiling, DFT, and molecular docking of novel 3-cyano-2-pyridone derivatives as dual EGFR and cytokine (TNF-α, IL-6) inhibitors (2025).

Research Area

الكيمياء العضوية