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Curriculum Vitae

Samy Megahed Ibrahiem Elsayed Sakr

Faculty pharmacy - Department Medicinal Chemistry Department

MSc In NULL, [1984]
(لا يوجد)
PhD In NULL, [1988]
(-)

Academic Jobs

معيد : 7/10/1979
Doctor Assisant : 13/6/1984
Doctor : 20/7/1988
Professor Assisant : 28/9/2004

Publications

1 - Synthesis Of Certain -4-Quinazolones Likely To Possess Pharmacological Activity

2 - ٍSynthesis And Biological Activity Of Some Novel Heterocyclic Compounds Containing Sulphar Of Pharmaceutical Interest

3 - Synthesis of New 2,3-Dihydroquinazolin-4(1H)-one Derivatives for Analgesic and Anti-inflammatory Evaluation (2010).

4 - Synthesis of new benzotriazepin-5(2H)-one derivatives of expected antipsychotic activity (2013).

5 - SYNTHESIS AND EVALUATION OF 2, 3-DIHYDROQUINAZOLIN-4(1H)-ONE DERIVATIVES AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS (2013).

6 - Synthesis of Some New Benzisothiazolone and Benzenesulfonamide Derivatives of Biological Interest Starting from Saccharin Sodium (2013).

7 - Synthesis of Some New Benzisothiazolone and Benzenesulfonamide Derivatives of Biological Interest Starting from Saccharin Sodium (2013).

8 - Synthesis and antiviral activity of new pyrazole and thiazole derivatives (2009).

9 - Synthesis of 125I‐lamivudine and 125I‐lamivudine‐ursodeoxycholic acid codrug (2016).

10 - Exploring the binding sites of Staphylococcus aureus phenylalanine tRNA synthetase: A homology model approach (2017).

11 - Synthesis and antimicrobial activity of newly synthesized 4-substituted-pyrazolo[3,4-d]pyrimidine derivatives (2017).

12 - Exploring the binding sites of Staphylococcus aureus phenylalanine tRNA synthetase: A homology model approach (2017).

13 - Functionalized polymer monoliths with carbamylated amylose for the enantioselective reversed phase nano-liquid chromatographic separation of a set of racemic pharmaceuticals (2017).

14 - Functionalized polymer monoliths with carbamylated amylose for the enantioselective reversed phase nano-liquid chromatographic separation of a set of racemic pharmaceuticals (2017).

15 - Synthesis, In vivo and In silico Evaluation of Novel 2,3-Dihydroquinazolin-4(1H)-one Derivatives as Potential Anticonvulsant Agents (2019).

16 - 1,4-Dihydroquinazolin-3(2H)-yl benzamide derivatives as anti-inﬂammatory and analgesic agents with an improved gastric proﬁle: Design, synthesis, COX-1/2 inhibitory activity and molecular docking study (2018).

17 - Toxicity Profile and Pharmacokinetic Study of Antibiotic Mixtures, Gentamicin and Vancomycin, in Rat Plasma by Ecofriendly Liquid Chromatography Coupled Tandem Mass Spectrometry (2020).

18 - Design and synthesis of novel quinazolinones conjugated ibuprofen, indole acetamide, or thioacetohydrazide as selective COX-2 inhibitors: anti-inflammatory, analgesic and anticancer activities (2021).

19 - Quinazolinone dimers as a potential new class of safer Kv1 inhibitors: Overcoming hERG, sodium and calcium channel affinities (2021).

20 - Quinazoline‐tethered hydrazone: A versatile scaffold toward dual anti‐TB and EGFR inhibition activities in NSCLC (2021).

21 - Synthesis of New 1,3-Benzodiazine and 1,3,4-Benzotriazepine Derivatives for Biological Study " تشييد مشتقات جديدة من 1و3 بنزوديازين و1و3و4 بنزوتريازيبين وذلك للدراسة البيولوجية (2024).

22 - " Quinazoline-related analogs as modulators of neurotransmitter receptors and transporters'' المتناظرات المتعلقة بالكينازولين كمتغيرات للمستقبلات والنواقل العصبية (2024).

23 - Design and Synthesis of Novel Phenylalanine tRNA Synthetase Inhibitors as Potential Therapeutics for the Treatment of MRSA Infections (2024).

24 - Synthesis and biological screening of new quinazolin-4(3H)-one and benzotriazepine derivatives (2024).

25 - Synthesis of New 2,3-dihydroquinazolinones and their Tricyclic Derivatives for Biological Evaluation (2024).

26 - Synthesis of 1, 2, 4‐triazole and 1, 3, 4‐oxadiazole derivatives as inhibitors for STAT3 enzymes of breast cancer (2023).

27 - Novel 2-[thio]acetamide linked quinazoline/1,2,4-triazole/chalcone hybrids: Design, synthesis, and anticancer activity as EGFR inhibitors and apoptotic inducers (2024).

28 - An overview of pyrazolo[3,4-d]pyrimidine heterocycles: recent synthetic approaches and biological activities (2025).

Research Area