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Samar Abdelmigeed Mohamed Rezk

Faculty pharmacy - Department Pharmacology and Toxicology Department

BSc In NULL, [2005]
MSc In NULL, [2010]
PhD In NULL, [2016]

قائم باجازة خاصة

Academic Jobs

معيد : 30/10/2005
Doctor Assisant : 26/4/2010
Doctor : 29/11/2016
استاذ مساعد لقب علمى : 25/7/2023

Publications

1 - Rostral Ventrolateral medulla EP3 receptor mediates the sympathoexcitatory and pressor effects of prostaglandin E2 in conscious rats (2016).

2 - Central GPR109A Activation Mediates Glutamate-Dependent Pressor Response in Conscious Rats. (2016).

3 - Synthesis, In vivo and In silico Evaluation of Novel 2,3-Dihydroquinazolin-4(1H)-one Derivatives as Potential Anticonvulsant Agents (2019).

4 - 1,4-Dihydroquinazolin-3(2H)-yl benzamide derivatives as anti-inﬂammatory and analgesic agents with an improved gastric proﬁle: Design, synthesis, COX-1/2 inhibitory activity and molecular docking study (2018).

5 - Albizia anthelmintica: HPLC-MS/MS profiling and in vivo anti-inflammatory, pain killing and antipyretic activities of its leaf extract (2019).

6 - Characterization of phenolic compounds from Eugenia supraaxillaris leaf extract using HPLCPDA- MS/MS and its antioxidant, anti-inflammatory, antipyretic and pain killing activities in vivo (2019).

7 - Chemical profiling of secondary metabolites of Eugenia uniflora and their antioxidant, anti-inflammatory, pain killing and anti-diabetic activities: A comprehensive approach (2019).

8 - Salix tetrasperma Roxb. Extract Alleviates Neuropathic Pain in Rats via Modulation of the NF-κB/TNF-α/NOX/iNOS Pathway (2019).

9 - Thymus algeriensis and Thymus fontanesii exert neuroprotective effect against chronic constriction injury-induced neuropathic pain in rats. (2020).

10 - Haematoxylon campechianum extract ameliorates neuropathic pain via inhibition of NF-κB/TNF-α/NOX/iNOS signaling pathway in a rat model of chronic constriction injury (2020).

11 - Thymus algeriensis and Thymus fontanesii: chemical composition, in vivo antiinflammatory, pain killing and antipyretic activities: A comprehensive comparison. (2020).

12 - Mechanisms Involved in Superiority of Angiotensin Receptor Blockade over ACE Inhibition in Attenuating Neuropathic Pain Induced in Rats (2020).

13 - Renin‐angiotensin system blockade modulates both the peripheral and central components of neuropathic pain in rats: Role of calcitonin gene–related peptide, substance P and nitric oxide (2020).

14 - Renal protective effect of nebivolol in rat models of acute renal injury: role of sodium glucose co-transporter 2 (2020).

15 - Doxazosin downregulates sodium‐glucose cotransporter‐2 (SGLT2) and exerts a renoprotective effect in rat models of acute renal injury (2019).

16 - CoQ10 exerts hepatoprotective effect in fructose-induced fatty liver model in rats (2020).

17 - Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inﬂammatory response via dual COX-2 and 15-LOX inhibition (2021).

18 - Design and synthesis of novel quinazolinones conjugated ibuprofen, indole acetamide, or thioacetohydrazide as selective COX-2 inhibitors: anti-inflammatory, analgesic and anticancer activities (2021).

19 - Anti-Inflammatory, Antipyretic, and Analgesic Properties of Potamogeton perfoliatus Extract: In Vitro and In Vivo Study (2021).

20 - Potamogeton perfoliatus L. Extract Attenuates Neuroinflammation and Neuropathic Pain in Sciatic Nerve Chronic Constriction Injury-Induced Peripheral Neuropathy in Rats (2021).

21 - Rimonabant ameliorates hepatic ischemia/reperfusion injury in rats: Involvement of autophagy via modulating ERK-and PI3K/ AKT-mTOR pathways (2021).

22 - Endogenous β-endorphin plays a pivotal role in angiotensin II-mediated central neurochemical changes and pressor response (2021).

23 - Vitamin E rescues valproic acid-induced testicular injury in rats: Role of autophagy (2022).

24 - Geraniol protects against cyclosporine A-induced renal injury in rats: Role of Wnt/β-catenin and PPARγ signaling pathways (2022).

25 - Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19 (2021).

26 - Syzygium aqueum: A polyphenol- rich leaf extract exhibits antioxidant, hepatoprotective, pain-killing and anti-inflammatory activities in animal models (2018).

27 - Triple targeting of mutant EGFRL858R/T790M, COX-2, and 15-LOX: design and synthesis of novel quinazolinone tethered phenyl urea derivatives for anti-inflammatory and anticancer evaluation (2023).

28 - Synthesis of new multitarget-directed ligands containing thienopyrimidine nucleus for inhibition of 15-lipoxygenase, cyclooxygenases, and pro-inflammatory cytokines (2023).

29 - الآليات المشتركة في تعديل نظام الرينين أنجيوتنسن لألام الأعصاب المحدثة في الفئران" "mechanisms involved in RAAS modulation of neuropathic pain induced in rats " (2024).

30 - HPLC-ESI-MS/MS Profiling of Polyphenolics of a Leaf Extract from Alpinia zerumbet (Zingiberaceae) and Its Anti-Inflammatory, Anti-Nociceptive, and Antipyretic … (2018).

31 - Moxonidine ameliorates cardiac injury in rats with metabolic syndrome by regulating autophagy (2023).

Research Area