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Curriculum Vitae

Ahmed Samy Abdelsamad Abdelkhalek hilal

Faculty pharmacy - Department Medicinal Chemistry Department

BSc In NULL, [2010]
MSc In NULL, [2014]
PhD In NULL, [2019]

قائم بالعمل

Academic Jobs

معيد : 10/2/2011
Doctor Assisant : 31/5/2014
Doctor : 30/4/2019

Publications

1 - SYNTHESIS AND EVALUATION OF 2, 3-DIHYDROQUINAZOLIN-4(1H)-ONE DERIVATIVES AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS (2013).

2 - Synthesis and biological screening of new derivatives of 2,3-dihydro quinazolin-4(1H)-one and benzotriazepin- 5(2H)-one for central nervous system activity (2014).

3 - “Methylene Bridge” to 5-HT3 Receptor Antagonists Conformationally Constrained Phenylguanidines (2018).

4 - Probing of 2-Amino-6-Chloro-3,4-Dihydroquinazoline Hydrochloride At 5- HT3 Receptor (2018).

5 - Probing of 2-Amino-6-Chloro-3,4-Dihydroquinazoline Hydrochloride At 5- HT3 Receptor (2018).

6 - X-ray crystal structure of a 2-amino-3, 4-dihydroquinazoline 5-HT3 serotonin receptor antagonist and related analogs (2020).

7 - Controlling of Bacterial Virulence: Evaluation of Anti-Virulence Activities of Prazosin against Salmonella enterica (2022).

8 - Evaluation of acute oral toxicity, anti-diabetic and antioxidant effects of Aloe vera flowers extract (2023).

9 - Pharmaceutical polymers and P-glycoprotein: Current trends and possible outcomes in drug delivery (2023).

10 - Synthesis of New 1,3-Benzodiazine and 1,3,4-Benzotriazepine Derivatives for Biological Study " تشييد مشتقات جديدة من 1و3 بنزوديازين و1و3و4 بنزوتريازيبين وذلك للدراسة البيولوجية (2024).

11 - " Quinazoline-related analogs as modulators of neurotransmitter receptors and transporters'' المتناظرات المتعلقة بالكينازولين كمتغيرات للمستقبلات والنواقل العصبية (2024).

12 - Triple targeting of mutant EGFRL858R/T790M, COX-2, and 15-LOX: design and synthesis of novel quinazolinone tethered phenyl urea derivatives for anti-inflammatory and anticancer evaluation (2023).

13 - Eco-friendly novel deconvoluted synchronous spectrofluorimetric approach for the determination of favipiravir, levodropropizine and moxifloxacin hydrochloride as an effective therapeutic combination for COVID-19; application in laboratory prepared mixtures and spiked human plasma (2023).

14 - The use of an RP-HPLC-UV method for the analysis of oxcarbazepine in the presence of its preservatives; stability studies and application to human plasma samples (2023).

15 - Magic shotgun approach to anti-inflammatory pharmacotherapy: Synthesis of novel thienopyrimidine monomers/heterodimer as dual COX-2 and 15-LOX inhibitors endowed with potent antioxidant activity (2023).

16 - Synthesis of new multitarget-directed ligands containing thienopyrimidine nucleus for inhibition of 15-lipoxygenase, cyclooxygenases, and pro-inflammatory cytokines (2023).

17 - GC-MS profiling and evaluation of acute oral toxicity, anti-tumour, antimicrobial and antioxidant activities of Croton socotranus Balf.f. aerial parts: in-vitro, in-vivo and in-silico studies (2023).

18 - Triazolopyrimidine Derivatives: An Updated Review on Recent Advances in Synthesis, Biological Activities and Drug Delivery Aspects (2024).

19 - Design and Synthesis of Novel Thienopyrimidine Derivatives with Potential Biological Activity (2024).

20 - Evaluation of acute oral toxicity, anti-diabetic and antioxidant effects of Aloe vera flowers extract (2023).

21 - An overview on 2-indolinone derivatives as anticancer agents (2024).

22 - Eco-friendly novel deconvoluted synchronous spectrofluorimetric approach for the determination of favipiravir, levodropropizine and moxifloxacin hydrochloride as an effective therapeutic combination for COVID-19; application in laboratory prepared mixtures and spiked human plasma (2024).

23 - Green chemometric-assisted UV-spectrophotometric methods for the determination of favipiravir, cefixime and moxifloxacin hydrochloride as an effective therapeutic combination for COVID-19; application in pharmaceutical form and spiked human plasma (2024).

24 - Dual COX-2 and 15-LOX inhibition study of novel 4-arylidine-2-mercapto-1-phenyl-1H-imidazolidin-5(4H)-ones: Design, synthesis, docking, and anti-inflammatory activity (2024).

25 - Novel 2-[thio]acetamide linked quinazoline/1,2,4-triazole/chalcone hybrids: Design, synthesis, and anticancer activity as EGFR inhibitors and apoptotic inducers (2024).

26 - Chemical Characterization, Evaluation of Acute Oral Toxicity, and Anti-Diabetic Activity of Aloe sabaea Flowers Extract on Alloxan-Induced Diabetic Rats (2024).

27 - A Lean Six Sigma approach aided improvement for simultaneous electrochemical determination of antiviral drug favipiravir and levodropropizine as an option in the treatment of COVID-19 using glassy carbon electrode modified NiFe2O4 nanocomposite in different matrices (2024).

28 - A Lean Six Sigma approach aided improvement for simultaneous electrochemical determination of antiviral drug favipiravir and levodropropizine as an option in the treatment of COVID-19 using glassy carbon electrode modified NiFe2O4 nanocomposite in different matrices (2024).

29 - Green chemometric-assisted UV-spectrophotometric methods for the determination of favipiravir, cefixime and moxifloxacin hydrochloride as an effective therapeutic combination for COVID-19; application in pharmaceutical form and spiked human plasma (2024).

30 - Ecofriendly spectrophotometric methods for simultaneous determination of remdesivir and moxifloxacin hydrochloride as co administered drugs in corona virus treatment (2025).

Research Area